Cytostatic Activity of Some Phenolic Acids of Scrophularia frutescens L. var. frutescens

نویسندگان

  • M. D. Garcia
  • M. C. Ahumada
  • M. T. Saenz
چکیده

M. D. Garcia, M. C. Ahumada and M. T. Saenz Departamento de Farmacologfa, Facultad de Farmacia, c/Profesor Garcia Gonzalez s/n, 41012 Sevilla, Spain Z. Naturforsch. 53c, 1093-1095 (1998); received April 8/October 7, 1998 Scrophularia frutescens. Cultured H ep-2 Cells, Cultured McCoy Cells, Phenolic Acids The cytostatic activity of seven phenolic acids: coumaric, caffeic, ferulic, gentisic, protocatechuic, syringic and isovanillic acid previously isolated from Scrophularia frutescens has been evaluated against H ep -2 cells (de­ rived from a human epidermoid carcinoma of the lar­ ynx) and McCoy cells (derived from the synovial fluid in the knee joint of a patient suffering from degenerative arthritis). The compounds belonging to the cinnamic group present the highest activity.

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تاریخ انتشار 1999